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Neuropilin-1 Antibodies
AND NRP1 ELISA kits, Neuropilin-1 Proteins
Many biological assays use antibodies to detect Neuropilin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuropilin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuropilin-1 antibodies...
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NRP1 Infographic by Boster Bio
All NRP1 Products
Product
Figures
Specificity
Applications
Price
Mouse Neuropilin-1 ELISA Kit PicoKine®
1 Citations 11 Q&As
Mouse
ELISA
$499
Cat # EK1342
96 wells/kit, with removable strips.
Cat # EK1342
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK1343
96 wells/kit, with removable strips.
Cat # EK1343
96 wells/kit, with removable strips.
Human Neuropilin-1 ELISA Kit PicoKine®
1 Citations 10 Q&As
Human
ELISA
$499
Cat # EK1353
96 wells/kit, with removable strips.
Cat # EK1353
96 wells/kit, with removable strips.
Anti-Neuropilin 1/NRP1 Antibody Picoband®
1 Citations 16 Q&As
Human, Rat
IHC, WB
$370
Cat # PB9300
100 μg/vial
Cat # PB9300
100 μg/vial
Anti-Neuropilin 1 NRP1 Rabbit Monoclonal Antibody
2 Citations 16 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01324
100 μl
Cat # M01324
100 μl
Anti-Neuropilin-1 NRP1 Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A01324
100ul
Cat # A01324
100ul
Human, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M01324-1
100 μg/vial
Cat # M01324-1
100 μg/vial
Human, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M01324-2
100 μg/vial
Cat # M01324-2
100 μg/vial
NRP1 Overview
Facts about Neuropilin-1.
Neuropilin-1 (NRP1)
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of specific neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant action of semaphorins.
It contrasts to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR in addition to increased chemotaxis.
Gene Information
| Human | |
|---|---|
| Gene Name: | NRP1 |
| Uniprot: | O14786 |
| Entrez: | 8829 |
Family
| Belongs to: |
|---|
| neuropilin family |
Alternative Names
BDCA4; BDCA-4; CD304 antigen; CD304; DKFZp686A03134; DKFZp781F1414; neuropilin 1; Neuropilin1; Neuropilin-1; NRP1; NRPNP1; transmembrane receptor; Vascular endothelial cell growth factor 165 receptor; VEGF165RCD304
Molecular Weight
Mass (kDA):
103.134 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p11.22 |
| Sequence: | 10; NC_000010.11 (33177491..33334905, complement) |
Tissue Specificity
The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.
Subcellular Localizations
[Isoform 2]: Secreted.; Mitochondrion membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Diseases
- Tumor Angiogenesis
- Neoplasms
- Malignant Neoplasms
- Pathologic Neovascularization
- Nervousness
- Neoplasm Metastasis
- Tissue Adhesions
- Carcinoma
- Tumor Progression
- Crest Syndrome
- Malignant Neoplasm Of Breast
- Inflammation
Interacting Proteins
- FLNA
- ITGA5
- KDR
- VEGFA
Pathways
- Angiogenesis
- Axon Guidance
- Cell Migration
- Cell Proliferation
- Localization
- Cell Adhesion
- Blood Vessel Development
- Vasculogenesis
- Regeneration
- Pathogenesis
- Chemotaxis
- Immune Response
- Tube Formation
PTMs
- Phosphorylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRP1
bosterbio.com/bosterbio-gene-info-cards/NRP1
References
PMID: 9288753 by He Z., et al. Neuropilin is a receptor for the axonal chemorepellent semaphorin III.
PMID: 9529250 by Soker S., et al. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.
4 Publications of Boster Neuropilin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1111/jdi.12542, Elevated expression levels of serum insulin‐like growth factor‐1, tumor necr...
- PubMed ID: -, Nedaei,K.,Hesaraki,M.,Mazloomzadeh,S.,Totonchi,M.,& Biglari,A.(2021).Lentiviral ...
- PubMed ID: 32035191, Wang Y,Yin S,Mei L,Yang Y,Xu S,He X,Wang M,Li M,Zhang Z,He Q.A dual receptors-ta...
- PubMed ID: 26877777, Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Effi...
*More publications can be found for each product on its corresponding product page