NOTO Antibodies

AND NOTO ELISA kits, NOTO Proteins

Many biological assays use antibodies to detect NOTO, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NOTO in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NOTO antibodies...

We validate the specificity of these antibodies to NOTO by testing them on tissues known to express NOTO positively and negatively. Browse below to find the NOTO antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NOTO Infographic by Boster Bio

All NOTO Products

Product

Figures

Specificity

Applications

Price

Anti-Mouse Noto Antibody (C-term)

Mouse

$298
Cat # M05571
80 µl

NOTO Overview

Facts about Homeobox protein notochord.

NOTO 3D structure. Source: alphafold

Homeobox protein notochord (NOTO)

Transcription regulator acting downstream of both FOXA2 and Brachyury (T) during notochord development. Required for node morphogenesis.

Is crucial for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of different components important for axonemal function and assembly. Plays a role in regulating axial versus paraxial cell fate (By similarity).

Gene Information

Human
Gene Name:	NOTO
Uniprot:	A8MTQ0
Entrez:	344022

Family

Belongs to:

No superfamily

Alternative Names

homeobox protein notochord; notochord homeobox

Molecular Weight

Mass (kDA):
27.003 kDA

Genomic Context


Human

Location:	2p13.2
Sequence:	2; NC_000002.12 (73202574..73212513)

Subcellular Localizations

Nucleus.

Diseases

Cataract
Stress, Psychological
Diabetes Mellitus
Lens Opacities
Depressive Disorder
Depression, Postpartum
Cataract Subcapsular
Radiation Injury
Fracture Of First Cervical Vertebra
Diabetic Nephropathy
Pregnancy Complications

Sensation Disorders
Kidney Neoplasm
Venous Thrombosis
Diabetic Angiopathies
Neoplasms
Hemorrhage

Pathways

Transport
Aging
Localization
Notochord Formation
Cell Adhesion
Gastrulation
Gene Silencing
Convergent Extension
Polyamine Transport
Virulence
Embryo Development

Translation
Cellular Localization
Axon Guidance
Spermine Transport
Rna Interference
Excretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOTO

References

PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.

PMID: 15815621 by Hillier L.W., et al. Generation and annotation of the DNA sequences of human chromosomes 2 and 4.