NAALAD2 Antibodies

AND NAALAD2 ELISA kits, NAALAD2 Proteins

Many biological assays use antibodies to detect NAALAD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAALAD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAALAD2 antibodies...

We validate the specificity of these antibodies to NAALAD2 by testing them on tissues known to express NAALAD2 positively and negatively. Browse below to find the NAALAD2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAALAD2 Infographic by Boster Bio

All NAALAD2 Products

Product

Figures

Specificity

Applications

Price

NAALAD2 (NM_005467) Human Recombinant Protein

$1249
Cat # PROTQ9Y3Q0
20 µg

NAALAD2 (NM_005467) Human Over-expression Lysate

Human

$960
Cat # LS010003
100 µg

NAALAD2 Overview

Facts about N-acetylated-alpha-linked acidic dipeptidase 2.

NAALAD2 3D structure. Source: alphafold

N-acetylated-alpha-linked acidic dipeptidase 2 (NAALAD2)

Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Also exhibits a dipeptidyl-peptidase IV type activity.

Inactivate the peptide neurotransmitter N- acetylaspartylglutamate. .

Gene Information

Human
Gene Name:	NAALAD2
Uniprot:	Q9Y3Q0
Entrez:	10003

Family

Belongs to:

peptidase M28 family

Alternative Names

GCPIII; Glutamate Carboxypeptidase III; GPCIII; MGC116996; MGC26353; NAADALASE2; NAALAD2; NAALADase II; NAALADase2; NAALADase-2; N-acetylated alpha-linked acidic dipeptidase 2; N-acetylated alpha-linked acidic dipeptidase II; N-acetylated-alpha-linked acidic dipeptidase 2; N-acetylated-alpha-linked acidic dipeptidase II

Molecular Weight

Mass (kDA):
83.592 kDA

Genomic Context


Human

Location:	11q14.3
Sequence:	11; NC_000011.10 (90131693..90193577)

Tissue Specificity

Highest expression in the testis. Also found in ovary and spleen. Weak expression in prostate, heart and placenta. In brain, expressed in striatum, parietal cortex and ventral striatum with lower levels in hippocampus, brain stem, putamen and superior colliculus.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.

Pathways

Pathogenesis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAALAD2

References

PMID: 10085079 by Pangalos M.N., et al. Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.

PMID: 19678840 by Hlouchova K., et al. Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.