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- Table of Contents
Facts about Aminopeptidase NAALADL1.
Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity).
Human | |
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Gene Name: | NAALADL1 |
Uniprot: | Q9UQQ1 |
Entrez: | 10004 |
Belongs to: |
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peptidase M28 family |
I100; ileal dipeptidylpeptidase; NAALADase L; NAALADase like 1; NAALADASEL; NAALADase-like 1; NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1; NAALADL1
Mass (kDA):
80.558 kDA
Human | |
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Location: | 11q13.1 |
Sequence: | 11; NC_000011.10 (65044818..65059020, complement) |
Mainly expressed in the distal small intestine. Also expressed in the spleen and testis. Weak expression in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. Isoform 2 and 3 isoform 3 are found in the small intestine and colon.
Apical cell membrane; Single-pass type II membrane protein. Ileal brush border membrane.
PMID: 10085079 by Pangalos M.N., et al. Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.
PMID: 9388249 by Shneider B.L., et al. Cloning and characterization of a novel peptidase from rat and human ileum.