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Nudt10 Antibodies
AND Nudt10 ELISA kits, Nudt10 Proteins
Many biological assays use antibodies to detect Nudt10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nudt10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nudt10 antibodies...
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Nudt10 Overview
Facts about Diphosphoinositol polyphosphate phosphohydrolase 3-alpha.
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (Nudt10)
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.
The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate; however, the relevance of such activity in vivo remains unclear.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nudt10 |
| Uniprot: | P0C027 |
| Entrez: | 102954 |
Family
| Belongs to: |
|---|
| Nudix hydrolase family |
Alternative Names
APS2DIPP3A; Diadenosine 5'-5'''-P1; diphosphoinositol polyphosphate phosphohydrolase 3-alpha; diphosphoinositol polyphosphate phosphohydrolase type 3 alpha; DIPP3a; DIPP-3-alpha; DIPP3-alpha; EC 3.6.1.-; EC 3.6.1.52; hDIPP3alphahAps2; Nucleoside diphosphate-linked moiety X motif 10; nudix (nucleoside diphosphate linked moiety X)-type motif 10; Nudix motif 10; P6-hexaphosphate hydrolase 3-alpha
Molecular Weight
Mass (kDA):
18.593 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | X|X A1.1 |
| Sequence: | X; |
Tissue Specificity
Mainly expressed in testis, liver kidney and, at lower level, in heart, brain, spleen, lung and skeletal muscle.
Diseases
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Malignant Neoplasms
- Endometrial Neoplasms
- Endometrial Carcinoma
- Endometrial Polyp
Pathways
- Reverse Transcription
- Dna Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nudt10
bosterbio.com/bosterbio-gene-info-cards/Nudt10
References
PMID: 12689335 by Hua L.V., et al. Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.