This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Nuclear migration protein nudC.
Necessary for cytokinesis and cell proliferation. .
Human | |
---|---|
Gene Name: | NUDC |
Uniprot: | Q9Y266 |
Entrez: | 10726 |
Belongs to: |
---|
nudC family |
HNUDC; MNUDC; NPD011; nuclear distribution gene C (A.nidulans) homolog; nuclear distribution gene C homolog (A. nidulans); Nuclear distribution protein C homolog; nuclear migration protein nudC; NudC
Mass (kDA):
38.243 kDA
Human | |
---|---|
Location: | 1p36.11 |
Sequence: | 1; NC_000001.11 (26900569..26946871) |
Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
Cytoplasm, cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
PMID: 10210332 by Miller B.A., et al. A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis.
PMID: 10453739 by Matsumoto N., et al. Molecular cloning and characterization of the human NUDC gene.