NUBP2 Antibodies

AND NUBP2 ELISA kits, NUBP2 Proteins

Many biological assays use antibodies to detect NUBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUBP2 antibodies...

We validate the specificity of these antibodies to NUBP2 by testing them on tissues known to express NUBP2 positively and negatively. Browse below to find the NUBP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUBP2 Infographic by Boster Bio

All NUBP2 Products

Product

Figures

Specificity

Applications

Price

NUBP2 (NM_012225) Human Recombinant Protein

$1249
Cat # PROTQ9Y5Y2
20 µg

NUBP2 (NM_012225) Human Over-expression Lysate

Human

$628
Cat # LS010101
100 µg

NUBP2 Overview

Facts about Cytosolic Fe-S cluster assembly factor NUBP2.

NUBP2 3D structure. Source: alphafold

Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2)

Part of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins.

The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S audience and its transfer to target apoproteins. Negatively regulates cilium formation and construction.

Gene Information

Human
Gene Name:	NUBP2
Uniprot:	Q9Y5Y2
Entrez:	10101

Family

Belongs to:

Mrp/NBP35 ATP-binding proteins family

Alternative Names

CFD1C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) ); cytosolic Fe-S cluster assembly factor NUBP2; homolog of yeast cytosolic Fe-S cluster deficient 1; NBP 2; NUBP1; nucleotide binding protein 2 (E.coli MinD like); nucleotide binding protein 2 (MinD homolog, E. coli); Nucleotide-binding protein 2

Molecular Weight

Mass (kDA):
28.825 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1782960..1789186)

Tissue Specificity

Widely expressed with highest expression in skeletal muscle.

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center. Enriched at the centrosomes during mitosis. Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis (By similarity). Localized at centrioles and in the nucleus at interphase (By similarity). Colocalizes with nubp-1 at prometaphase (By similarity).

Diseases

Chromosome Breakage

Interacting Proteins

KRTAP10-7
NOTCH2NL
TNS2

Pathways

Centrosome Duplication
Rna Interference
Ribosome Biogenesis
Cell Cycle
Mitosis
Cell Growth
Interphase
Regulation Of Centrosome Duplication
Iron-sulfur Cluster Assembly

Localization
Spindle Assembly
Cytokinesis

PTMs

Carboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUBP2

References

PMID: 10486206 by Nakashima H., et al. Two novel mouse genes -- Nubp2, mapped to the T-complex on chromosome 17, and Nubp1, mapped to chromosome 16 -- establish a new gene family of nucleotide-binding proteins in eukaryotes.

PMID: 18573874 by Stehling O., et al. Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.