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NQO1 Antibodies
AND NQO1 ELISA kits, NQO1 Proteins
Many biological assays use antibodies to detect NQO1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NQO1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NQO1 antibodies...
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NQO1 Infographic by Boster Bio
All NQO1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00494
100 μl
Cat # M00494
100 μl
NQO1 Overview
Facts about NAD(P)H dehydrogenase [quinone] 1.
NAD(P)H dehydrogenase [quinone] 1 (NQO1)
The enzyme apparently functions as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways in addition to in biosynthetic processes like the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NQO1 |
| Uniprot: | P15559 |
| Entrez: | 1728 |
Family
| Belongs to: |
|---|
| NAD(P)H dehydrogenase (quinone) family |
Alternative Names
Azoreductase; DHQU; DIA4; DIA4azoreductase; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase-4; Dioxin-inducible 1; DTD; DTDEC 1.6.5.2; DT-diaphorase; Menadione Reductase; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NMOR1; NMOR1diaphorase-4; NQO1; NQO-1; Phylloquinone reductase; QR1; QR1NMORI; Quinone Reductase 1
Molecular Weight
Mass (kDA):
30.868 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (69709401..69726560, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinogenesis
- Leukemia
- Carcinoma
- Inflammation
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Adenocarcinoma
- Liver Carcinoma
- Mammary Neoplasms
- Myeloid Leukemia
Interacting Proteins
- ING1
Pathways
- Cell Death
- Pathogenesis
- Cell Cycle
- Dna Repair
- Aging
- Cell Proliferation
- Transport
- Cell Growth
- Localization
- Conjugation
- Methylation
- Electron Transport
- Excretion
PTMs
- Phosphorylation
- Reduction
- Oxidation
- Cleavage
- Methylation
- Ubiquitination
- Demethylation
- Acetylation
Research Areas
- Cancer
- Cellular Markers
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NQO1
bosterbio.com/bosterbio-gene-info-cards/NQO1
References
PMID: 2843525 by Jaiswal A.K., et al. Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.
PMID: 1657151 by Jaiswal A.K.; Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin.