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- Table of Contents
Facts about NADPH oxidase organizer 1.
Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. .
Mouse | |
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Gene Name: | Noxo1 |
Uniprot: | Q8VCM2 |
Entrez: | 71893 |
Belongs to: |
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No superfamily |
MGC20258; NADPH oxidase organizer 1; Nox organizer 1; Nox-organizing protein 1; P41NOX; P41NOXA; P41NOXB; P41NOXC; regulatory protein P41NOX; SH3 and PX domain-containing protein 5; SH3PXD5NADPH oxidase regulatory protein; SNX28
Mass (kDA):
38.827 kDA
Mouse | |
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Location: | 17 A3.3|17 12.49 cM |
Sequence: | 17; |
Strongly expressed by colon epithelial cells and to a lower extent in small intestine, uterus, stomach and testis. Expressed in different parts of the inner ear including sensory and nonsensory cell layers of the saccule, ampullae of the semicircular canals, the stria vascularis and the spiral glanglion neurons.
PMID: 12473664 by Banfi B., et al. Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
PMID: 15949904 by Cheng G., et al. Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3.