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NADPH oxidase 5 Antibodies
AND NOX5 ELISA kits, NADPH oxidase 5 Proteins
Many biological assays use antibodies to detect NADPH oxidase 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NADPH oxidase 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NADPH oxidase 5 antibodies...
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NOX5 Infographic by Boster Bio
All NOX5 Products
Product
Figures
Specificity
Applications
Price
Anti-NADPH oxidase 5 NOX5 Antibody Picoband®
1 Citations 3 Q&As
Human
IHC, ICC, WB
$370
Cat # PA1947
100 μg/vial
Cat # PA1947
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03119
100 μg/vial
Cat # A03119
100 μg/vial
NOX5 Overview
Facts about NADPH oxidase 5.
NADPH oxidase 5 (NOX5)
Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and might regulate redox-dependent procedures in lymphocytes and spermatozoa.
May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial production of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Gene Information
| Human | |
|---|---|
| Gene Name: | NOX5 |
| Uniprot: | Q96PH1 |
| Entrez: | 79400 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EC 1.6.3.-; MGC149776; MGC149777; NADPH oxidase 5; NADPH oxidase, EF-hand calcium binding domain 5; NOX5A; NOX5B
Molecular Weight
Mass (kDA):
86.439 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q23 |
| Sequence: | 15; NC_000015.10 (68930525..69062762) |
Tissue Specificity
Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Subcellular Localizations
Membrane; Multi-pass membrane protein.; [Isoform v2]: Endoplasmic reticulum.; [Isoform v5]: Endoplasmic reticulum.
Diseases
- Adenocarcinoma
- Esophageal Adenocarcinoma
- Esophageal Neoplasms
- Barrett Esophagus
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Gastroesophageal Reflux Disease
- Cell Transformation, Neoplastic
- Atherosclerosis
- Carcinoma
- Injury To Kidney
- Dysplasia
Pathways
- Cell Proliferation
- Localization
- Transport
- Electron Transport
- Respiratory Burst
- Pathogenesis
- Aging
- Cell Cycle
- Senescence
- Acrosome Reaction
- Cellular Localization
- Cell Growth
- Angiogenesis
PTMs
- Phosphorylation
- Nitration
- Nitrosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOX5
bosterbio.com/bosterbio-gene-info-cards/NOX5
References
PMID: 11483596 by Banfi B., et al. A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes.
PMID: 15994299 by Kawahara T., et al. Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.
1 Publications of Boster NADPH oxidase 5 Antibodies & ELISA Kits
- PubMed ID: 28099519, Jafari N1, Kim H1,2, Park R1,2, Li L1, Jang M1,2, Morris AJ3, Park J1,2, Huang C...
*More publications can be found for each product on its corresponding product page