Nostrin Antibodies

AND NOSTRIN ELISA kits, Nostrin Proteins

Many biological assays use antibodies to detect Nostrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nostrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nostrin antibodies...

We validate the specificity of these antibodies to Nostrin by testing them on tissues known to express NOSTRIN positively and negatively. Browse below to find the NOSTRIN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: ALPK2

NOSTRIN Infographic by Boster Bio

All NOSTRIN Products

Product

Figures

Specificity

Applications

Price

Anti-NOSTRIN Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A06014
0.1 mg

NOSTRIN (NM_001039724) Human Recombinant Protein

$1249
Cat # PROTQ8IVI9
20 µg

Anti-NOSTRIN Mouse Monoclonal Antibody [Clone ID: OTI3B1]

Human

$523
Cat # M06014
100 µl

NOSTRIN (NM_052946) Human Over-expression Lysate

Human

$628
Cat # LS115677
100 µg

NOSTRIN Overview

Facts about Nostrin.

NOSTRIN 3D structure. Source: alphafold

Nostrin (NOSTRIN)

Multivalent adapter protein which might decrease NOS3 activity by inducing its translocation from the plasma membrane. .

Gene Information

Human
Gene Name:	NOSTRIN
Uniprot:	Q8IVI9
Entrez:	115677

Family

Belongs to:

No superfamily

Alternative Names

BM247 homolog; DaIP2; endothelial nitric oxide synthase traffic inducer; ENOS traffic inducer; eNOS-trafficking inducer; Nitric oxide synthase traffic inducer; nitric oxide synthase traffickerMGC20702; nitric oxide synthase trafficking; nostrin; ortholog of mouse disabled 2 interacting proein 2

Molecular Weight

Mass (kDA):
57.66 kDA

Genomic Context


Human

Location:	2q24.3
Sequence:	2; NC_000002.12 (168786539..168865514)

Tissue Specificity

Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over- expressed in placenta from women with pre-eclampsia (at protein level).

Subcellular Localizations

[Isoform 1]: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Enriched in selected actin structures (PubMed:16234328, PubMed:16376344).; [Isoform 3]: Nucleus.

Diseases

Hypertensive Disease
Pre-eclampsia
Inflammation
Hepatitis, Alcoholic
Coronary Heart Disease
Otitis Media
Hypoxia
Teratocarcinoma
Sequelae Aspects
Otitis Media Acute
Hypertension Induced By Pregnancy
Hypokinesia
Cardiovascular Diseases

Tumor Angiogenesis
Azoospermia
Ear Inflammation
Pulmonary Hypertension
Bacterial Infections
Hypertension, Portal
Infective Disorder

Interacting Proteins

DNM1
FGFR1
NOS3
Wasl

Pathways

Localization
Pathogenesis
Cell Adhesion
Endocytosis
Nuclear Export
Spermatogenesis
Senescence
Cell Differentiation
Membrane Fission

Angiogenesis
Exocytosis
Actin Nucleation
Nuclear Import

PTMs

Nitration

Phosphorylation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOSTRIN

References

PMID: 12446846 by Zimmermann K., et al. NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.

PMID: 11489260 by Kirsch T., et al. Altered gene expression in cerebral capillaries of stroke-prone spontaneously hypertensive rats.