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- Table of Contents
Facts about Neuroligin-4, X-linked.
Human | |
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Gene Name: | NLGN4X |
Uniprot: | Q8N0W4 |
Entrez: | 57502 |
Belongs to: |
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type-B carboxylesterase/lipase family |
ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260AUTSX2; MGC22376; neuroligin 4, X-linked; Neuroligin 4X; NL4; NLGN; NLGN4; NLGN4neuroligin 4; NLGN4X; X-linked
Mass (kDA):
91.915 kDA
Human | |
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Location: | Xp22.32-p22.31 |
Sequence: | X; NC_000023.11 (5890026..6228878, complement) |
Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain.
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.
PMID: 12669065 by Jamain S., et al. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
PMID: 9278515 by Irie M., et al. Binding of neuroligins to PSD-95.