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- Table of Contents
Facts about Neuroligin-3.
May promote the first formation of synapses, but isn't vital for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).
Human | |
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Gene Name: | NLGN3 |
Uniprot: | Q9NZ94 |
Entrez: | 54413 |
Belongs to: |
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type-B carboxylesterase/lipase family |
ASPGX1; AUTSX1; Gliotactin homolog; HNL3; KIAA1480HNL3; Neuroligin 3; neuroligin-3; NL3; NLGN3
Mass (kDA):
93.895 kDA
Human | |
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Location: | Xq13.1 |
Sequence: | X; NC_000023.11 (71144389..71175307) |
Expressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells.
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Detected at both glutamatergic and GABAergic synapses.
PMID: 10767552 by Philibert R.A., et al. The structure and expression of the human neuroligin-3 gene.
PMID: 20034102 by Rissone A., et al. Characterization of the neuroligin gene family expression and evolution in zebrafish.