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- Table of Contents
Facts about Formin-2.
Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2.
Mouse | |
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Gene Name: | Fmn2 |
Uniprot: | Q9JL04 |
Entrez: | 54418 |
Belongs to: |
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formin homology family |
Formin-2
Mass (kDA):
167.387 kDA
Mouse | |
---|---|
Location: | 1 H3|1 81.04 cM |
Sequence: | 1; |
Detected in brain and in oocytes (at protein level). Expressed almost exclusively in the developing and mature central nervous system. Detected in oocytes.
PMID: 10781961 by Leader B., et al. Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system.
PMID: 12447394 by Leader B., et al. Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes.