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Nkap Antibodies
AND Nkap ELISA kits, Nkap Proteins
Many biological assays use antibodies to detect Nkap, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nkap in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nkap antibodies...
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Nkap Infographic by Boster Bio
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Nkap Overview
Facts about NF-kappa-B-activating protein.
NF-kappa-B-activating protein (Nkap)
Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of this Notch-mediated signaling needed for T-cell development.
Also involved in the TNF and IL-1 triggered NF-kappa-B activation. Associates with chromatin in the Notch-regulated SKP2 promoter (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nkap |
| Uniprot: | Q9D0F4 |
| Entrez: | 67050 |
Family
| Belongs to: |
|---|
| NKAP family |
Alternative Names
FLJ22626; NF-kappaB activating protein; NF-kappa-B-activating protein; NFKB activating protein
Molecular Weight
Mass (kDA):
47.227 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | X|X A3.3 |
| Sequence: | X; |
Diseases
- Retinal Degeneration
- Hepatitis
- Inflammation
- Dog Diseases
- Retinitis Pigmentosa
Pathways
- Senescence
- Reverse Transcription
- Cell Development
- Aging
- Megakaryocyte Development
- Cell Maturation
PTMs
- Acetylation
- Isopeptide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nkap
bosterbio.com/bosterbio-gene-info-cards/Nkap
References
PMID: 14550261 by Chen D., et al. Identification of a nuclear protein that promotes NF-kappaB activation.