Nuclear factor 1 A-type Antibodies

AND NFIA ELISA kits, Nuclear factor 1 A-type Proteins

Many biological assays use antibodies to detect Nuclear factor 1 A-type, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nuclear factor 1 A-type in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nuclear factor 1 A-type antibodies...

We validate the specificity of these antibodies to Nuclear factor 1 A-type by testing them on tissues known to express NFIA positively and negatively. Browse below to find the NFIA antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NFIA Infographic by Boster Bio

All NFIA Products

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Product

Figures

Specificity

Applications

Price

Anti-NFIA Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, ICC, WB

$370
Cat # PB10080
100 μg/vial

Anti-NFIA Antibody Picoband® (monoclonal, 16H11)

6 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03531
100 μg/vial

Nuclear Factor 1 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1786
1 kit, containing one 96-well plate and all necessary reagents

Nuclear Factor 1 (NFIA) (NM_005595) Human Recombinant Protein

$813
Cat # PROTQ12857
20 µg

Anti-NFIA Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03531
100 μg/vial

NFIA Overview

Facts about Nuclear factor 1 A-type.

NFIA 3D structure. Source: alphafold

Nuclear factor 1 A-type (NFIA)

Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

Gene Information

Human
Gene Name:	NFIA
Uniprot:	Q12857
Entrez:	4774

Family

Belongs to:

CTF/NF-I family

Alternative Names

CCAAT-box-binding transcription factor; CTF; DKFZp686J23256; FLJ39164; KIAA1439DKFZp434L0422; NF1-A; NF-I/A; NFI-A; NFI-L; nuclear factor 1 A-type; Nuclear factor 1/A; nuclear factor I/ATGGCA-binding protein

Molecular Weight

Mass (kDA):
55.944 kDA

Genomic Context


Human

Location:	1p31.3
Sequence:	1; NC_000001.11 (61077227..61462788)

Subcellular Localizations

Nucleus.

Diseases

Nervousness
Neoplasms
Congenital Absence
Hydrocephalus
Mammary Neoplasms
Neurofibromatosis 1
Malignant Paraganglionic Neoplasm
Haploinsufficiency
Agenesis Of Corpus Callosum
(balanced Rearrangements Or Structural Markers Nec) Or (balanced Translocations)
Chromosomal Translocation
Tissue Adhesions

Loss Of Chromosome 1
Glioma
Myeloid Leukemia, Chronic
Macrocephaly
Congenital Neurologic Anomalies
Hypoplasia
Cell Transformation, Neoplastic

Pathways

Dna Replication
Neurogenesis
Gliogenesis
Axon Guidance
Cell Differentiation
Cell Proliferation
Brain Development
Regulation Of Gene Expression
Rna Splicing
Cell Adhesion
Pathogenesis
Gene Silencing
Translation

Localization
Cell Death
Cell Migration
Developmental Process
Ossification
Mammary Gland Development
Myelination

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFIA

References

PMID: 7590749 by Qian F., et al. Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

PMID: 24462883 by Rao A., et al. An intragenic deletion of the NFIA gene in a patient with a hypoplastic corpus callosum, craniofacial abnormalities and urinary tract defects.