NET1 Antibodies

AND NET1 ELISA kits, NET1 Proteins

Many biological assays use antibodies to detect NET1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NET1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NET1 antibodies...

We validate the specificity of these antibodies to NET1 by testing them on tissues known to express NET1 positively and negatively. Browse below to find the NET1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NET1 Infographic by Boster Bio

All NET1 Products

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Product

Figures

Specificity

Applications

Price

Anti-ARHG8 NET1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A02618
100ul

NET1 (NM_001047160) Human Over-expression Lysate

Human

$960
Cat # LS010276
100 µg

NET1 Overview

Facts about Neuroepithelial cell-transforming gene 1 protein.

NET1 3D structure. Source: alphafold

Neuroepithelial cell-transforming gene 1 protein (NET1)

Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB action in breast cancer cells leading to their cell death.

Gene Information

Human
Gene Name:	NET1
Uniprot:	Q7Z628
Entrez:	10276

Family

Belongs to:

No superfamily

Alternative Names

ARHGEF8neuroepithelial cell-transforming gene 1 protein; guanine nucleotide regulatory protein (oncogene); NET1A; neuroepithelial cell transforming 1; neuroepithelial cell transforming gene 1; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor (GEF) 8; Rho guanine nucleotide exchange factor 8; small GTP-binding protein regulator

Molecular Weight

Mass (kDA):
67.74 kDA

Genomic Context


Human

Location:	10p15.1
Sequence:	10; NC_000010.11 (5412557..5459056)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Attention Deficit Hyperactivity Disorder
Carcinoma
Neoplasms
Malnutrition
Malignant Neoplasm Of Breast
Mammary Neoplasms
Liver Carcinoma
Neoplasm Invasiveness
Liver Neoplasms
Adenocarcinoma
Cell Invasion
Stomach Neoplasms

Neoplasm Metastasis
Gastric Adenocarcinoma
Neuroectodermal Tumors
Tissue Adhesions
Malignant Neoplasm Of Stomach
Malignant Tumor Of Cervix
Dysequilibrium Syndrome

Interacting Proteins

DLG1
SCRIB

Pathways

Anaphase
Cell Cycle
Mitosis
Localization
Exit From Mitosis
Telophase
Chromosome Segregation
Cell Migration
Cell Division
Interphase
Metaphase
Cell Adhesion
Nuclear Export

Cytokinesis
Cell Proliferation
Dna Replication
Gene Silencing
Cell Death
Cell Growth
M Phase

PTMs

Phosphorylation
Dephosphorylation
Deacetylation

Cleavage
Acetylation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NET1

References

PMID: 8649828 by Chan A.M.-L., et al. Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning.

PMID: 11278519 by Shen X., et al. The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation.