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NEK9 Antibodies
AND NEK9 ELISA kits, NEK9 Proteins
Many biological assays use antibodies to detect NEK9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEK9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEK9 antibodies...
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NEK9 Infographic by Boster Bio
All NEK9 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$335
Cat # P04660
100ul
Cat # P04660
100ul
Human, Mouse, Rat
ELISA
$480
Cat # EKC1397
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1397
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2320
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2320
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M04660
100 µl
Cat # M04660
100 µl
NEK9 Overview
Facts about Serine/threonine-protein kinase Nek9.
Serine/threonine-protein kinase Nek9 (NEK9)
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2.
Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
Gene Information
| Human | |
|---|---|
| Gene Name: | NEK9 |
| Uniprot: | Q8TD19 |
| Entrez: | 91754 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
DKFZp434D0935; KIAA1995; MGC138306; MGC16714; NEK8; Nek8NERCC1; Nercc1 kinase; NERCCEC 2.7.11.1; Never in mitosis A-related kinase 9; NIMA (never in mitosis gene a)- related kinase 9; NimA-related kinase 8; NIMA-related kinase Nek8; NimA-related protein kinase 9; serine/threonine-protein kinase Nek9
Molecular Weight
Mass (kDA):
107.168 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.3 |
| Sequence: | 14; NC_000014.9 (75079353..75127637, complement) |
Tissue Specificity
Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Polycystic Kidney Diseases
- Kidney Diseases
- Instabilities, Chromosomal
- Malignant Squamous Cell Neoplasm
- Tongue Neoplasms
- Primary Neoplasm
- Head And Neck Carcinoma
- Aneuploidy
- Cystic Kidney Diseases
Interacting Proteins
- DYNLL1
- GABARAP
- GABARAPL1
- GABARAPL2
- HSP90AB1
- MAP1LC3B
- MAP1LC3C
- PLK1
Pathways
- Mitosis
- Cell Cycle
- Spindle Assembly
- Spindle Organization
- Cytokinesis
- Spindle Assembly Checkpoint
- Chromosome Segregation
- Anaphase
- Cell Division
- Prophase
- Metaphase
- Localization
- Protein Phosphorylation
PTMs
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- DNA Repair
- GPCR
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEK9
bosterbio.com/bosterbio-gene-info-cards/NEK9
References
PMID: 11864968 by Holland P.M., et al. Purification, cloning, and characterization of Nek8, a novel NIMA- related kinase, and its candidate substrate Bicd2.
PMID: 12101123 by Roig J., et al. Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression.