Nek7 Antibodies

AND Nek7 ELISA kits, Nek7 Proteins

Many biological assays use antibodies to detect Nek7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nek7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nek7 antibodies...

We validate the specificity of these antibodies to Nek7 by testing them on tissues known to express Nek7 positively and negatively. Browse below to find the Nek7 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nek7 Infographic by Boster Bio

All Nek7 Products

Product

Figures

Specificity

Applications

Price

Anti-Nek7 Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # A04996
100ul

Human NEK7 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ8TDX7
Starting from 20ug

Anti-NEK7 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M04996
100 μl/vial

NEK7 (NM_133494) Human Over-expression Lysate

Human

$628
Cat # LS140609
100 µg

Nek7 Overview

Facts about Serine/threonine-protein kinase Nek7.

Serine/threonine-protein kinase Nek7 (Nek7)

Protein kinase that plays an significant role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis.

Phosphorylates RPS6KB1. .

Gene Information

Mouse
Gene Name:	Nek7
Uniprot:	Q9ES74
Entrez:	59125

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11.1; Never in mitosis A-related kinase 7; NIMA (never in mitosis gene a)-related kinase 7; NimA-related protein kinase 7; serine/threonine-protein kinase Nek7

Molecular Weight

Mass (kDA):
34.537 kDA

Genomic Context


Mouse

Location:	1 E4\|1 60.82 cM
Sequence:	1;

Diseases

Malignant Neoplasms
Instabilities, Chromosomal
Cell Transformation, Neoplastic
Developmental Delay (disorder)
Polyploidy
Tissue Adhesions
Malignant Neoplasm Of Liver
Aneuploidy
Malignant Neoplasm Of Urinary Bladder
Malignant Neoplasm Of Lung
Carcinoma
Carcinogenesis
Growth Retardation

Wolf-hirschhorn Syndrome
Polycystic Kidney Diseases
Neoplasms
Tetraploidy
Nervousness
Chromosomal Translocation
Chromosome Breakage

Pathways

Mitosis
Cell Cycle
Spindle Assembly
Cytokinesis
Cell Division
Spindle Organization
Centrosome Separation
Spindle Assembly Checkpoint
Metaphase
Cell Adhesion
Proteolysis
M Phase
Anaphase

Cell Cycle Arrest
Microtubule Nucleation
Prophase
Chromatin Organization
Histone Lysine Methylation
Centrosome Cycle
Interphase

PTMs

Phosphorylation

Research Areas

GPCR
Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nek7

References

PMID: 10964517 by Kandli M., et al. Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and Nek7) related to the fungal mitotic regulator, NIMA.

PMID: 20473324 by Salem H., et al. Nek7 kinase targeting leads to early mortality, cytokinesis disturbance and polyploidy.