NEDD4 Antibodies

AND NEDD4 ELISA kits, NEDD4 Proteins

Many biological assays use antibodies to detect NEDD4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEDD4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEDD4 antibodies...

We validate the specificity of these antibodies to NEDD4 by testing them on tissues known to express NEDD4 positively and negatively. Browse below to find the NEDD4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEDD4 Infographic by Boster Bio

All NEDD4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NEDD4 Antibody Picoband®

15 Q&As

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00984-2
100 μg/vial

Anti-NEDD4 Antibody

Human

IHC, WB

$405
Cat # A00984
100ul

Anti-NEDD4 Rabbit Monoclonal Antibody

1 Citations 15 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IHC, WB

$370
Cat # M00984
100 μl

Anti-NEDD4 Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A00984-3
100 μg/vial

Anti-Nedd4 Antibody Picoband®

Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A00984-4
100 μg/vial

NEDD4 (NM_006154) Human Over-expression Lysate

Human

$960
Cat # LS004734
100 µg

NEDD4 Overview

Facts about E3 ubiquitin-protein ligase NEDD4.

NEDD4 3D structure. Source: alphafold

E3 ubiquitin-protein ligase NEDD4 (NEDD4)

Specifically ubiquitinates'Lys-63' in target proteins (PubMed:23644597). Involved in the pathway resulting in the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity.

Monoubiquitinates IGF1R at multiple sites, thus resulting in receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, resulting in receptor internalization and degradation in lysosomes.

Gene Information

Human
Gene Name:	NEDD4
Uniprot:	P46934
Entrez:	4734

Family

Belongs to:

No superfamily

Alternative Names

Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; EC 6.3.2; EC 6.3.2.-; KIAA0093NEDD4-1MGC176705; NEDD4; NEDD-4; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; receptor-potentiating factor 1; RPF1

Molecular Weight

Mass (kDA):
149.114 kDA

Genomic Context


Human

Location:	15q21.3
Sequence:	15; NC_000015.10 (55826917..55993612, complement)

Subcellular Localizations

Cytoplasm. Cell membrane; Peripheral membrane protein. Recruited to the plasma membrane by GRB10. Once complexed with GRB10 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). May be recruited to exosomes by NDFIP1.