NDUFS2 Antibodies

AND NDUFS2 ELISA kits, NDUFS2 Proteins

Many biological assays use antibodies to detect NDUFS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS2 antibodies...

We validate the specificity of these antibodies to NDUFS2 by testing them on tissues known to express NDUFS2 positively and negatively. Browse below to find the NDUFS2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFS2 Infographic by Boster Bio

All NDUFS2 Products

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Product

Figures

Specificity

Applications

Price

Anti-NDUFS2 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05618
100ul

NDUFS2 (NM_004550) Human Recombinant Protein

$813
Cat # PROTO75306
20 µg

Anti-NDUFS2 Mouse Monoclonal Antibody [Clone ID: OTI1D5]

Human, Mouse, Rat

IHC, WB

$523
Cat # M05618
100 µl

Anti-NDUFS2 Antibody (Center)

Human, Mouse

IHC-P, WB

$299
Cat # A05618-1
80 µl

Anti-NDUFS2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M05618-1
100 μl/vial

Anti-NDUFS2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05618-3
100 μg/vial

NDUFS2 (NM_004550) Human Over-expression Lysate

Human

$628
Cat # LS004720
100 µg

NDUFS2 Overview

Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial.

NDUFS2 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (NDUFS2)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is thought to belong to the minimal assembly required for catalysis. Sophisticated I works in the transport of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:12611891). .

Gene Information

Human
Gene Name:	NDUFS2
Uniprot:	O75306
Entrez:	4720

Family

Belongs to:

complex I 49 kDa subunit family

Alternative Names

CI-49; CI-49kD; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; Complex I-49kD; EC 1.6.5.3; EC 1.6.99.3; EC 1.6.99.5; NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit

Molecular Weight

Mass (kDA):
52.546 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161197417..161214395)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Leigh Disease
Cardiomyopathies
Parkinson Disease
Mitochondrial Diseases
Mitochondrial Encephalomyopathies
Acidosis
Nerve Degeneration
Obesity
Acidosis, Lactic
Optic Atrophy
Sclerosis

Leukoencephalopathy, Progressive Multifocal
Inborn Errors Of Metabolism
Weakness
Neurodegenerative Disorders
Leukoencephalopathies
Malignant Neoplasms

Interacting Proteins

NDUFS3

Pathways

Oxidative Phosphorylation
Translation
Transport
Cell Proliferation
Electron Transport
Aging
Proteolysis
Neurogenesis
Pigmentation
Thermotaxis
Phototaxis

Localization
Gliogenesis
Cell Death
Pathogenesis
Glycolysis

PTMs

Phosphorylation

Oxidation

Nitration

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS2

References

PMID: 9647766 by Loeffen J., et al. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

PMID: 9585441 by Procaccio V., et al. Mapping to 1q23 of the human gene (NDUFS2) encoding the 49-kDa subunit of the mitochondrial respiratory complex I and immunodetection of the mature protein in mitochondria.