NDUFS3 Antibodies

AND NDUFS3 ELISA kits, NDUFS3 Proteins

Many biological assays use antibodies to detect NDUFS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS3 antibodies...

We validate the specificity of these antibodies to NDUFS3 by testing them on tissues known to express NDUFS3 positively and negatively. Browse below to find the NDUFS3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFS3 Infographic by Boster Bio

All NDUFS3 Products

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Product

Figures

Specificity

Applications

Price

Anti-NDUFS3 Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M05867
100 μl

Anti-NDUFS3 Antibody

Human

IP, IF, IHC, ICC, WB

$405
Cat # A05867-1
100ul

Human NDUFS3 Recombinant Protein

SDS-PAGE

$350
Cat # PROTO75489
Starting from 10ug

Anti-NDUFS3 Antibody (C-term)

Human, Mouse

$299
Cat # A05867
80 µl

NDUFS3 (NM_004551) Human Over-expression Lysate

Human

$628
Cat # LS004722
100 µg

NDUFS3 Overview

Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial.

NDUFS3 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (NDUFS3)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimum assembly required for catalysis. Complex I works in the transport of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). .

Gene Information

Human
Gene Name:	NDUFS3
Uniprot:	O75489
Entrez:	4722

Family

Belongs to:

complex I 30 kDa subunit family

Alternative Names

CI-30; CI-30kD; complex I 30kDa subunit; Complex I-30kD; EC 1.6.5.3; EC 1.6.99.3; EC 1.6.99.5; NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit

Molecular Weight

Mass (kDA):
30.242 kDA

Genomic Context


Human

Location:	11p11.2
Sequence:	11; NC_000011.10 (47579074..47584562)

Subcellular Localizations

Mitochondrion inner membrane.

Diseases

Malignant Neoplasms
Mitochondrial Diseases
Carcinoma
Neoplasms
Diabetes Mellitus
Diabetes Mellitus, Experimental
Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Mammary Neoplasms
Parkinson Disease
Malignant Neoplasm Of Breast
Kidney Neoplasm
Renal Cell Carcinoma

Diabetes Mellitus, Insulin-dependent
Ductal Carcinoma
Hypokinesia
Neuroblastoma
Schizophrenia
Optic Atrophy
Diabetic Nephropathy

Interacting Proteins

NDUFA5
NDUFA8
NDUFS2

Pathways

Cell Death
Oxidative Phosphorylation
Translation
Transport
Electron Transport
Localization
Mitochondrial Translation
Electron Transport Chain
Nadh Oxidation
Membrane Hyperpolarization
Insulin Secretion
Proteolysis
Mitochondrial Dna Replication

Dna Replication
Respiratory Electron Transport Chain
Heart Formation
System Development
Organ Development
Nervous System Development
Iron-sulfur Cluster Assembly

PTMs

Phosphorylation
Cleavage

Oxidation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS3

References

PMID: 9647766 by Loeffen J., et al. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

PMID: 10967146 by Procaccio V., et al. Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial Complex I: genomic organization and expression.