NDUFS1 Antibodies

AND NDUFS1 ELISA kits, NDUFS1 Proteins

Many biological assays use antibodies to detect NDUFS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS1 antibodies...

We validate the specificity of these antibodies to NDUFS1 by testing them on tissues known to express NDUFS1 positively and negatively. Browse below to find the NDUFS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFS1 Infographic by Boster Bio

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Anti-NDUFS1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A04920
100ul

NDUFS1 Overview

Facts about NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial.

NDUFS1 3D structure. Source: alphafold

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is thought to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a part of the iron-sulfur (IP) fragment of the enzyme.

Gene Information

Human
Gene Name:	NDUFS1
Uniprot:	P28331
Entrez:	4719

Family

Belongs to:

complex I 75 kDa subunit family

Alternative Names

CI-75k; CI-75Kd; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; Complex I-75kD; EC 1.6.5.3; EC 1.6.99.3; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Qreductase); NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; PRO1304

Molecular Weight

Mass (kDA):
79.468 kDA

Genomic Context


Human

Location:	2q33.3
Sequence:	2; NC_000002.12 (206114817..206159444, complement)

Subcellular Localizations

Mitochondrion inner membrane.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Mitochondrial Diseases
Leigh Disease
Parkinson Disease
Mitochondrial Encephalomyopathies
Leukoencephalopathies
Nervous System Disorder
Malignant Neoplasms
Acidosis
Hereditary Diseases
Acidosis, Lactic
Neuroblastoma

Encephalopathies
Cardiomyopathies
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lung
Melanoma
Malignant Neoplasm Of Breast

Pathways

Oxidative Phosphorylation
Pathogenesis
Transport
Electron Transport
Electron Transport Chain
Localization
Aging
Mitochondrial Outer Membrane Permeabilization
Fertilization
Dna Repair
Swimming
Translation

Cell Cycle
Protein Folding
Iron-sulfur Cluster Assembly
Rna Interference
Glycolysis
Protein Ubiquitination

PTMs

Phosphorylation
Deacetylation

Cleavage
Acetylation

Ubiquitination

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS1

References

PMID: 1935949 by Chow W., et al. Determination of the cDNA sequence for the human mitochondrial 75-kDa Fe-S protein of NADH-coenzyme Q reductase.

PMID: 11349233 by Benit P., et al. Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency.