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- Table of Contents
Facts about Natural cytotoxicity triggering receptor 3 ligand 1.
Human | |
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Gene Name: | NCR3LG1 |
Uniprot: | Q68D85 |
Entrez: | 374383 |
Belongs to: |
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No superfamily |
B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; NCR3LG1
Mass (kDA):
50.827 kDA
Human | |
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Location: | 11p15.1 |
Sequence: | 11; NC_000011.10 (17351800..17377341) |
Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level).
Cell membrane; Single-pass type I membrane protein.
PMID: 19528259 by Brandt C.S., et al. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans.
PMID: 21422170 by Li Y., et al. Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6.