Neuron navigator 3 Antibodies

AND NAV3 ELISA kits, Neuron navigator 3 Proteins

Many biological assays use antibodies to detect Neuron navigator 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuron navigator 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuron navigator 3 antibodies...

We validate the specificity of these antibodies to Neuron navigator 3 by testing them on tissues known to express NAV3 positively and negatively. Browse below to find the NAV3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAV3 Infographic by Boster Bio

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Anti-Neuron navigator 3 NAV3 Antibody

Human

IHC

$380
Cat # A07567
100ul

NAV3 Overview

Facts about Neuron navigator 3.

NAV3 3D structure. Source: alphafold

Neuron navigator 3 (NAV3)

May regulate IL2 production by T-cells.
May be involved in neuron regeneration.

Gene Information

Human
Gene Name:	NAV3
Uniprot:	Q8IVL0
Entrez:	89795

Family

Belongs to:

Nav/unc-53 family

Alternative Names

KIAA0938pore membrane and/or filament interacting like protein 1; neuron navigator 3; POMFIl1; POMFIL1steerin 3; Pore membrane and/or filament-interacting-like protein 1; STEERIN3; steerin-3; Unc-53 homolog 3; unc53H3

Molecular Weight

Mass (kDA):
255.648 kDA

Genomic Context


Human

Location:	12q21.2
Sequence:	12; NC_000012.12 (77571856..78213010)

Tissue Specificity

Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.

Subcellular Localizations

Nucleus outer membrane.

Diseases

Neoplasms
Malignant Neoplasms
Skin Neoplasms
Lymphoma
T-cell Lymphoma
Influenza
Lymphoma, T-cell, Cutaneous
Carcinoma
Mycoses
Mycosis Fungoides
Malignant Paraganglionic Neoplasm
Sezary Syndrome

Cytogenetic Abnormality
Glioblastoma
Adenoma
Influenza In Birds
Inflammation
Neurodegenerative Disorders
Nervousness

Pathways

Axon Guidance
Pathogenesis
Regeneration
Reverse Transcription
Gene Silencing
Cell Cycle
Immune Response
Interphase
Viral Replication

Localization
Liver Development
Cell Fate Specification

PTMs

Phosphoprotein

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAV3

References

PMID: 15158073 by Peeters P.J., et al. Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

PMID: 12079279 by Maes T., et al. Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.