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- Table of Contents
1 Citations 16 Q&As
Facts about Homeobox protein NANOG.
Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'.
Mouse | |
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Gene Name: | Nanog |
Uniprot: | Q80Z64 |
Entrez: | 71950 |
Belongs to: |
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Nanog homeobox family |
FLJ12581; FLJ40451; hNanog; homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox; Nanog
Mass (kDA):
34.24 kDA
Mouse | |
---|---|
Location: | 6|6 F1 |
Sequence: | 6; |
Not expressed in oocytes and spermatogonia (at protein level). Not expressed in many somatic organs, ovary, testis, fibroblast and hematopoietic cell lines.
PMID: 12787504 by Mitsui K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.
PMID: 12787505 by Chambers I., et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.
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