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NAF1 Antibodies

AND NAF1 ELISA kits, NAF1 Proteins

Many biological assays use antibodies to detect NAF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAF1 antibodies...

We validate the specificity of these antibodies to NAF1 by testing them on tissues known to express NAF1 positively and negatively. Browse below to find the NAF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAF1 Infographic by Boster Bio

NAF1 protein infographic

All NAF1 Products

Product

Figures

Specificity

Applications

Price

NAF1 (NM_138386) Human Over-expression Lysate

Human

$628
Cat # LS092345
100 µg

Anti-NAF1 Antibody Picoband™

Human

ELISA, WB

$370
Cat # A02629-1
100 µg/vial

NAF1 Overview

Facts about H/ACA ribonucleoprotein complex non-core subunit NAF1.

NAF1 3D structure

NAF1 3D structure. Source: alphafold

H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is substituted by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex.

Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. .

Gene Information

Human
Gene Name:	NAF1
Uniprot:	Q96HR8
Entrez:	92345

Gene Information

Family

Belongs to:

NAF1 family

Family

Alternative Names

nuclear assembly factor 1 homolog (S. cerevisiae)

Molecular Weight

Mass (kDA):
53.717 kDA

Molecular Weight

Genomic Context


Human

Location:	4q32.2
Sequence:	4; NC_000004.12 (163109133..163166910, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus (By similarity).

Subcellular Localization

Diseases

Dyskeratosis Congenita
Dyskeratosis
Immunologic Deficiency Syndromes
Acquired Immunodeficiency Syndrome
Neoplasms
Leukemia
Liver Diseases
Dyslipidemias
Dihydropyrimidinase Deficiency
X-linked Dyskeratosis Congenita
Hematopoietic Neoplasms
Degenerative Polyarthritis
Leukemia, Myelocytic, Acute

Arthropathy
Brucella Abortus Infection
Myeloid Leukemia
Steroid Sulfatase Deficiency Disease
Rheumatoid Arthritis
Hematologic Neoplasms
Tissue Adhesions

Disease

Interacting Proteins

DAB1
DKC1
Dkc1
FAM168A
RBFOX2

SNX33

Interacting Proteins

Pathways

Pathogenesis
Ribosome Biogenesis
Telomere Maintenance
Transport
Pseudouridine Synthesis
Snorna Transcription
Localization
Rna Splicing
Reverse Transcription

Cell Death
Cell Cycle
Cell Growth
Box H/aca Snornp Assembly

Pathways

PTMs

Phosphorylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAF1

References

PMID: 16618814 by Darzacq X., et al. Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.

PMID: 16601202 by Hoareau-Aveilla C., et al. hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase.