MOCOS Antibodies

AND MOCOS ELISA kits, MOCOS Proteins

Many biological assays use antibodies to detect MOCOS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MOCOS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MOCOS antibodies...

We validate the specificity of these antibodies to MOCOS by testing them on tissues known to express MOCOS positively and negatively. Browse below to find the MOCOS antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MOCOS Infographic by Boster Bio

All MOCOS Products

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Specificity

Applications

Price

MOCOS (NM_017947) Human Recombinant Protein

$813
Cat # PROTQ96EN8
20 µg

MOCOS (NM_017947) Human Over-expression Lysate

Human

$628
Cat # LS055034
100 µg

MOCOS Overview

Facts about Molybdenum cofactor sulfurase.

MOCOS 3D structure. Source: alphafold

Molybdenum cofactor sulfurase (MOCOS)

Sulfurates the molybdenum cofactor. Sulfation of molybdenum is vital for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. .

Gene Information

Human
Gene Name:	MOCOS
Uniprot:	Q96EN8
Entrez:	55034

Family

Belongs to:

class-V pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

FLJ20733; HMCS; MCSEC 4.4; molybdenum cofactor sulfurase; MOSMoCo sulfurase

Molecular Weight

Mass (kDA):
98.12 kDA

Genomic Context


Human

Location:	18q12.2
Sequence:	18; NC_000018.10 (36187497..36272157)

Diseases

Hereditary Xanthinuria
Deficiency Of Xanthine Oxidase
Inflammatory Bowel Diseases
Medication Reaction
Hypouricaemia
Urolithiasis
Nerve Degeneration

Columnar Cell Change Of The Breast
Intestinal Diseases

Interacting Proteins

PARVA

Pathways

Excretion

PTMs

Nitration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MOCOS

References

PMID: 11302742 by Ichida K., et al. Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II.

PMID: 16973608 by Havemeyer A., et al. Identification of the missing component in the mitochondrial benzamidoxime prodrug converting system as a novel molybdenum enzyme.