Rab effector MyRIP Antibodies

AND MYRIP ELISA kits, Rab effector MyRIP Proteins

Many biological assays use antibodies to detect Rab effector MyRIP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rab effector MyRIP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rab effector MyRIP antibodies...

We validate the specificity of these antibodies to Rab effector MyRIP by testing them on tissues known to express MYRIP positively and negatively. Browse below to find the MYRIP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYRIP Infographic by Boster Bio

All MYRIP Products

Product

Figures

Specificity

Applications

Price

MYRIP (NM_015460) Human Over-expression Lysate

Human

$960
Cat # LS025924
100 µg

MYRIP Overview

Facts about Rab effector MyRIP.

MYRIP 3D structure. Source: alphafold

Rab effector MyRIP (MYRIP)

Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A.

May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP).

Gene Information

Human
Gene Name:	MYRIP
Uniprot:	Q8NFW9
Entrez:	25924

Family

Belongs to:

No superfamily

Alternative Names

DKFZp586F1018; exophilin-8; FLJ44025; MGC130034; myosin VIIA and Rab interacting protein; Myosin-VIIa- and Rab-interacting protein; MyRIP; rab effector MyRIP; SLAC2-C; SLAC2CMGC130035; Slp homolog lacking C2 domains c; Slp homologue lacking C2 domains; synaptotagmin-like protein homologue lacking C2 domains-c

Molecular Weight

Mass (kDA):
95.706 kDA

Genomic Context


Human

Location:	3p22.1
Sequence:	3; NC_000003.12 (39808914..40260321)

Subcellular Localizations

Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle. In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments.

Diseases

Neoplasm Recurrence, Local
Complete Hearing Loss
Liver Carcinoma
Melanoma
Neurodegenerative Disorders
Hypopigmentation-immunodeficiency Disease
Hepatocarcinogenesis
Autoimmune Diseases
Blind Vision
Carcinoma
Usher Syndrome
Age Related Macular Degeneration
Vascular System Injuries

Maculopathy
Autoimmune Reaction
Neoplasms
Peripheral Neuropathy
Azoospermia
Pheochromocytoma
Inflammation

Interacting Proteins

C1orf216

Pathways

Exocytosis
Transport
Secretion
Localization
Melanosome Transport
Vesicle Transport
Insulin Secretion
Hormone Secretion
Proteolysis
Dna Methylation

Pigmentation
Methylation
Pathogenesis
Hemostasis
Rna Interference

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYRIP

References

PMID: 11964381 by El-Amraoui A., et al. MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.

PMID: 12221080 by Fukuda M., et al. Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin.