Unconventional myosin-Ig Antibodies

AND MYO1G ELISA kits, Unconventional myosin-Ig Proteins

Many biological assays use antibodies to detect Unconventional myosin-Ig, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Unconventional myosin-Ig in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Unconventional myosin-Ig antibodies...

We validate the specificity of these antibodies to Unconventional myosin-Ig by testing them on tissues known to express MYO1G positively and negatively. Browse below to find the MYO1G antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYO1G Infographic by Boster Bio

All MYO1G Products

Product

Figures

Specificity

Applications

Price

Anti-Myosin 1G MYO1G Antibody

6 Q&As

Human

ELISA, WB

$599
Cat # A08448
100ug

Myosin 1G (MYO1G) (NM_033054) Human Over-expression Lysate

Human

$960
Cat # LS064005
100 µg

Anti-MYO1G Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08448-2
100 µg/vial

MYO1G Overview

Facts about Unconventional myosin-Ig.

MYO1G 3D structure. Source: alphafold

Unconventional myosin-Ig (MYO1G)

Unconventional myosin required during immune reaction for detection of infrequent antigen-presenting cells by regulating T- cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and function in intracellular movements.

Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens through lymph-node surveillance, enabling pathogen eradication. Also required in B- cells, where it regulates different membrane/cytoskeleton- dependent procedures.

Gene Information

Human
Gene Name:	MYO1G
Uniprot:	B0I1T2
Entrez:	64005

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

Unconventional myosin-Ig

Molecular Weight

Mass (kDA):
116.442 kDA

Genomic Context


Human

Location:	7p13
Sequence:	7; NC_000007.14 (44962662..44979105, complement)

Tissue Specificity

Specifically expressed in hematopoietic cells.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cell projection, phagocytic cup. Recruited to Fc-gamma receptor (Fc-gamma-R) phagocytic cup. In T-cells, transiently accumulates in discrete areas at the plasma membrane of migrating cells or when membranes are deformed (By similarity). Localization at the membrane is not highly dependent on phosphatidylinositol 4,5-bisphosphate levels. Released from the membrane in the presence of ATP. May be enriched in peripheral processes, such as microvilli or ruffles.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYO1G

References

PMID: 11544309 by Pierce R.A., et al. The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.

PMID: 7539551 by den Haan J.M.M., et al. Identification of a graft versus host disease-associated human minor histocompatibility antigen.