Myo18a Antibodies

AND Myo18a ELISA kits, Myo18a Proteins

Many biological assays use antibodies to detect Myo18a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myo18a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myo18a antibodies...

We validate the specificity of these antibodies to Myo18a by testing them on tissues known to express Myo18a positively and negatively. Browse below to find the Myo18a antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Myo18a Infographic by Boster Bio

All Myo18a Products

Product

Figures

Specificity

Applications

Price

Anti-Unconventional myosin-XVIIIa MYO18A Antibody

Human, Mouse, Rat

$405
Cat # A02344
100ul

Anti-MYO18A Mouse Monoclonal Antibody [Clone ID: OTI3F7]

Human, Mouse, Rat

IHC, WB

$523
Cat # M02344
100 µl

Myo18a Overview

Facts about Unconventional myosin-XVIIIa.

Unconventional myosin-XVIIIa (Myo18a)

May link Golgi membranes into the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and might indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035).

Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in regulating lamellar actomyosin retrograde flow that's imperative to cell protrusion and migration (By similarity). May be involved in the maintenance of the stromal cell architectures necessary for cell to cell contact (PubMed:10733906).

Gene Information

Mouse
Gene Name:	Myo18a
Uniprot:	Q9JMH9
Entrez:	360013

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

KIAA0216DKFZp686L0243; MAJN; Molecule associated with JAK3 N-terminus; myosin 18A; Myosin containing a PDZ domain; myosin containing PDZ domain; myosin XVIIIA; myosin-XVIIIa; MysPDZ; SP-A receptor subunit SP-R210 alphaS; SPR210

Molecular Weight

Mass (kDA):
232.755 kDA

Genomic Context


Mouse

Location:	11\|11 B5
Sequence:	11;

Tissue Specificity

Isoform 1; Expressed ubiquitously. Isoform 2: Specifically expressed in most hematopoietic cells. Isoform 3: Predominantly expressed in alveolar macrophages (PubMed:25965346).

Diseases

Tissue Adhesions
Carcinoma
Neoplasms
Myelodysplastic-myeloproliferative Diseases
Malignant Squamous Cell Neoplasm
Protrusion
Myeloproliferative Disease
Chromosomal Translocation
Hydrocephalus
Malignant Neoplasm Of Lung
Myeloid And Lymphoid Neoplasms With Fgfr1 Rearrangement
Leukemia, Myelocytic, Acute
Malignant Neoplasms

Myeloid Leukemia
Malignant Neoplasm Of Ovary
Hirschsprung Disease
Cytogenetic Abnormality
Myotonic Dystrophy
Eosinophilia
Cell Invasion

Pathways

Localization
Cell Migration
Cell Motility
Transport
Cell Adhesion
Virion Assembly
Secretory Pathway
Golgi Localization
Cell Development
Muscle Contraction
Macrophage Differentiation
Response To Uv

Cellular Localization
Cell Death
Pathogenesis
Innervation
Secretion
Epithelial Cell Migration

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Myo18a

References

PMID: 10733906 by Furusawa T., et al. Isolation of a novel PDZ-containing myosin from hematopoietic supportive bone marrow stromal cell lines.

PMID: 16087679 by Yang C.H., et al. Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A.