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- Table of Contents
Facts about c-Myc-binding protein.
.
Human | |
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Gene Name: | MYCBP |
Uniprot: | Q99417 |
Entrez: | 26292 |
Belongs to: |
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AMY1 family |
AMY-1AMY1; Associate of Myc 1; associate of myc-1; c-myc binding protein; C-Myc-binding protein; FLJ41056
Mass (kDA):
11.967 kDA
Human | |
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Location: | 1p34.3 |
Sequence: | 1; NC_000001.11 (38862490..38873378, complement) |
Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Cytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.
PMID: 9797456 by Taira T., et al. AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC.
PMID: 11483602 by Furusawa M., et al. AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP- dependent protein kinase.