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- Table of Contents
Facts about Matrix-remodeling-associated protein 5.
Human | |
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Gene Name: | MXRA5 |
Uniprot: | Q9NR99 |
Entrez: | 25878 |
Belongs to: |
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No superfamily |
Matrix-remodeling-associated protein 5
Mass (kDA):
312.15 kDA
Human | |
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Location: | Xp22.33 |
Sequence: | X; NC_000023.11 (3308565..3346652, complement) |
Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751).
Secreted.
PMID: 15609104 by Chondrogianni N., et al. Cloning of differentially expressed genes in skin fibroblasts from centenarians.
PMID: 27599751 by Poveda J., et al. MXRA5 is a TGF-beta1-regulated human protein with anti-inflammatory and anti-fibrotic properties.