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- Table of Contents
Facts about Crossover junction endonuclease MUS81.
May be required in mitosis for the processing of stalled or collapsed replication forks. .
Mouse | |
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Gene Name: | Mus81 |
Uniprot: | Q91ZJ0 |
Entrez: | 71711 |
Belongs to: |
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XPF family |
crossover junction endonuclease MUS81; EC 3.1.22; EC 3.1.22.-; FLJ21012; FLJ44872; MUS81 endonuclease homolog (S. cerevisiae); MUS81 endonuclease homolog (yeast); SLX3 structure-specific endonuclease subunit homolog; SLX3
Mass (kDA):
61.531 kDA
Mouse | |
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Location: | 19|19 A |
Sequence: | 19; |
Expressed highly in testis. Expressed also in bone marrow, brain, thymus and to a lesser extent in heart and skeletal muscle, colon, kidney and spleen.
PMID: 11741546 by Chen X.-B., et al. Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.
PMID: 14609959 by Abraham J., et al. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.