MT-ND4 Antibodies

AND MT-ND4 ELISA kits, MT-ND4 Proteins

Many biological assays use antibodies to detect MT-ND4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MT-ND4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MT-ND4 antibodies...

We validate the specificity of these antibodies to MT-ND4 by testing them on tissues known to express MT-ND4 positively and negatively. Browse below to find the MT-ND4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MT-ND4 Infographic by Boster Bio

All MT-ND4 Products

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Product

Figures

Specificity

Applications

Price

Anti-MT-ND4 Antibody Picoband®

1 Q&As

Human

ELISA, WB

$370
Cat # A04180-1
100 μg/vial

Anti-MT-ND4 Antibody

Human, Mouse, Rat

$405
Cat # A04180
100ul

MT-ND4 Overview

Facts about NADH-ubiquinone oxidoreductase chain 4.

MT-ND4 3D structure. Source: alphafold

NADH-ubiquinone oxidoreductase chain 4 (MT-ND4)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). .

Gene Information

Human
Gene Name:	MT-ND4
Uniprot:	P03905
Entrez:

Family

Belongs to:

complex I subunit 4 family

Alternative Names

ND4

Molecular Weight

Mass (kDA):
51.581 kDA

Genomic Context


Human

Location:
Sequence:	;

Subcellular Localizations

Mitochondrion membrane; Multi-pass membrane protein.

Diseases

Optic Atrophy, Hereditary, Leber
Disorder Of The Optic Nerve
Optic Atrophies, Hereditary
Visual Impairment
Blind Vision
Mitochondrial Diseases
Neoplasms
Optic Atrophy
Atrophy
Malignant Neoplasms
Aortic Aneurysm, Thoracic
Multiple Sclerosis

Sclerosis
Hypoxia
Carcinoma
Demyelination
Demyelinating Diseases
Leigh Disease

Pathways

Oxidative Phosphorylation
Transport
Cell Death
Pathogenesis
Electron Transport
Aging
Translation
Electron Transport Chain
Localization
Cell Cycle
Mating
Dna Replication
Sperm Motility

Programmed Cell Death
Immune Response
Pigmentation
Hypersensitivity
Inflammatory Response
Rna Processing
Rna Interference

PTMs

Phosphorylation
Oxidation
Methylation

Nitration
Cleavage
Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MT-ND4

References

PMID: 7219534 by Anderson S., et al. Sequence and organization of the human mitochondrial genome.

PMID: 1377597 by Lu X., et al. Differentiation of HT-29 human colonic adenocarcinoma cells correlates with increased expression of mitochondrial RNA: effects of trehalose on cell growth and maturation.