MSL3 Antibodies

AND MSL3 ELISA kits, MSL3 Proteins

Many biological assays use antibodies to detect MSL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MSL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MSL3 antibodies...

We validate the specificity of these antibodies to MSL3 by testing them on tissues known to express MSL3 positively and negatively. Browse below to find the MSL3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MSL3 Infographic by Boster Bio

All MSL3 Products

Product

Figures

Specificity

Applications

Price

MSL3L1 (MSL3) (NM_078629) Human Recombinant Protein

$1249
Cat # PROTQ8N5Y2
20 µg

MSL3L1 (MSL3) (NM_078629) Human Over-expression Lysate

Human

$628
Cat # LS010943
100 µg

Anti-MSL3 Antibody Picoband™

Human

ELISA, WB

$370
Cat # A04993-1
100 µg/vial

MSL3 Overview

Facts about Male-specific lethal 3 homolog.

MSL3 3D structure. Source: alphafold

Male-specific lethal 3 homolog (MSL3)

May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation.

Component of the MSL complex which is responsible for nearly all histone H4 acetylation in'Lys-16' that is implicated in the creation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated in'Lys-20' (H4K20Me1) at a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.

Gene Information

Human
Gene Name:	MSL3
Uniprot:	Q8N5Y2
Entrez:	10943

Family

Belongs to:

No superfamily

Alternative Names

male-specific lethal 3 homolog (Drosophila); male-specific lethal 3 homolog; male-specific lethal 3-like 1 (Drosophila); male-specific lethal-3 (Drosophila)-like 1; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL3L1DKFZp586J1822; MSL3-like 1

Molecular Weight

Mass (kDA):
59.824 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (11758159..11775772)

Tissue Specificity

Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.

Subcellular Localizations

Nucleus.

Diseases

Multiple Organ Failure
Tuberculosis
Cell Transformation, Neoplastic
Strongyloidiasis
Infectious Mononucleosis
Aicardi's Syndrome
Tense
Neoplasms
Focal Dermal Hypoplasia

Salmonella Infections
Eosinophilia
Trematode Infections

Pathways

Dosage Compensation
Localization
Transport
Virulence
Histone H4 Acetylation
Cell Cycle
Pathogenesis
Chromosome Localization
Eye Pigmentation
Photosynthesis
Pigmentation
Histone Modification
Sex Determination

Sexual Reproduction
Cell Cycle Arrest
Cellular Response To Osmotic Stress
Senescence
Response To Osmotic Stress
Protein Complex Assembly
Chromatin Remodeling

PTMs

Acetylation

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MSL3

References

PMID: 10395802 by Prakash S.K., et al. Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3.

PMID: 16227571 by Smith E.R., et al. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.