This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about ER lumen protein-retaining receptor 1.
COPI-coated transport intermediates, either in the form of round vesicles or as tubular procedures, mediate retrograde visitors of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi.
Human | |
---|---|
Gene Name: | KDELR1 |
Uniprot: | P24390 |
Entrez: | 10945 |
Belongs to: |
---|
ERD2 family |
ER lumen protein retaining receptor 1; ERD2; ERD2.1KDEL receptor 1; HDEL; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; PM23; Putative MAPK-activating protein PM23
Mass (kDA):
24.542 kDA
Human | |
---|---|
Location: | 19q13.33 |
Sequence: | 19; NC_000019.10 (48382575..48391551, complement) |
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
PMID: 2172835 by Lewis M.J., et al. A human homologue of the yeast HDEL receptor.
PMID: 12761501 by Matsuda A., et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.