This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
1 Citations 5 Q&As
Facts about DNA mismatch repair protein Msh2.
When bound, heterodimers bend the DNA helix and protects approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) from the DNA.
Human | |
---|---|
Gene Name: | MSH2 |
Uniprot: | P43246 |
Entrez: | 4436 |
Belongs to: |
---|
DNA mismatch repair MutS family |
COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC; HNPCC1; HNPCC1mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1); LCFS2; MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); MutS protein homolog 2
Mass (kDA):
104.743 kDA
Human | |
---|---|
Location: | 2p21-p16.3 |
Sequence: | 2; NC_000002.12 (47403067..47634501) |
Ubiquitously expressed.
Nucleus. Chromosome.
PMID: 8252616 by Fishel R., et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
PMID: 8261515 by Leach F.S., et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.
*More publications can be found for each product on its corresponding product page