MRS2 Antibodies

AND MRS2 ELISA kits, MRS2 Proteins

Many biological assays use antibodies to detect MRS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MRS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MRS2 antibodies...

We validate the specificity of these antibodies to MRS2 by testing them on tissues known to express MRS2 positively and negatively. Browse below to find the MRS2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MRS2 Infographic by Boster Bio

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MRS2 (NM_020662) Human Over-expression Lysate

Human

$960
Cat # LS057380
100 µg

MRS2 Overview

Facts about Magnesium transporter MRS2 homolog, mitochondrial.

MRS2 3D structure. Source: alphafold

Magnesium transporter MRS2 homolog, mitochondrial (MRS2)

Magnesium transporter that mediates the influx of magnesium to the mitochondrial matrix (PubMed:11401429, PubMed:18384665). Required for normal expression of the mitochondrial respiratory complex I subunits (PubMed:18384665).

Gene Information

Human
Gene Name:	MRS2
Uniprot:	Q9HD23
Entrez:	57380

Family

Belongs to:

CorA metal ion transporter (MIT) (TC 1.A.35) family

Alternative Names

HPT; MGC78523; mitochondrial; MRS2 magnesium homeostasis factor homolog (S. cerevisiae); MRS2-like protein; MRS2-like, magnesium homeostasis factor (S. cerevisiae); MRS2-like, magnesium homeostasis factor

Molecular Weight

Mass (kDA):
50.318 kDA

Genomic Context


Human

Location:	6p22.3
Sequence:	6; NC_000006.12 (24402908..24426194)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Nervousness
Stomach Neoplasms
Mitochondrial Diseases
Hereditary Diseases
Demyelination
Suppressor Mutation
Parkinson Disease
Growth Retardation
Congenital Disorders
Patient Dependence On

Malignant Neoplasm Of Stomach
Malignant Neoplasms
Hypertrophy
Magnesium Deficiency
Demyelinating Diseases

Pathways

Transport
Group Ii Intron Splicing
Rna Splicing
Translation
Cell Cycle
Cell Death
Cell Growth
Fertilization
Ion Transport
Cation Homeostasis
Oxidative Phosphorylation

Myelination
Cell Cycle Arrest
Drug Resistance
Swimming
Mitochondrial Translation
Pathogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MRS2

References

PMID: 11401429 by Zsurka G., et al. The human mitochondrial Mrs2 protein functionally substitutes for its yeast homologue, a candidate magnesium transporter.

PMID: 18384665 by Piskacek M., et al. Conditional knockdown of hMRS2 results in loss of mitochondrial Mg(2+) uptake and cell death.