MRM1 Antibodies

AND MRM1 ELISA kits, MRM1 Proteins

Many biological assays use antibodies to detect MRM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MRM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MRM1 antibodies...

We validate the specificity of these antibodies to MRM1 by testing them on tissues known to express MRM1 positively and negatively. Browse below to find the MRM1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MRM1 Infographic by Boster Bio

All MRM1 Products

Product

Figures

Specificity

Applications

Price

MRM1 (NM_024864) Human Recombinant Protein

$1249
Cat # PROTQ6IN84
20 µg

MRM1 (NM_024864) Human Over-expression Lysate

Human

$628
Cat # LS079922
100 µg

MRM1 Overview

Facts about rRNA methyltransferase 1, mitochondrial.

MRM1 3D structure. Source: alphafold

rRNA methyltransferase 1, mitochondrial (MRM1)

S-adenosyl-L-methionine-dependent two'-O-ribose methyltransferase that catalyzes the formation of 2'-O- methylguanosine at stake 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. .

Gene Information

Human
Gene Name:	MRM1
Uniprot:	Q6IN84
Entrez:	79922

Family

Belongs to:

class IV-like SAM-binding methyltransferase superfamily

Alternative Names

EC 2.1.1.-; FLJ22578; Mitochondrial large ribosomal RNA ribose methylase; mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae); rRNA methyltransferase 1, mitochondrial

Molecular Weight

Mass (kDA):
38.638 kDA

Genomic Context


Human

Location:	17q12
Sequence:	17; NC_000017.11 (36601583..36634698)

Subcellular Localizations

Mitochondrion.

Interacting Proteins

AGTRAP
CGGBP1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MRM1

References

PMID: 24036117 by Lee K.W., et al. Mitochondrial ribosomal RNA (rRNA) methyltransferase family members are positioned to modify nascent rRNA in foci near the mitochondrial DNA nucleoid.

PMID: 25074936 by Lee K.W., et al. Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16S rRNA.