MRGPRX3 Antibodies

AND MRGPRX3 ELISA kits, MRGPRX3 Proteins

Many biological assays use antibodies to detect MRGPRX3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MRGPRX3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MRGPRX3 antibodies...

We validate the specificity of these antibodies to MRGPRX3 by testing them on tissues known to express MRGPRX3 positively and negatively. Browse below to find the MRGPRX3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MRGPRX3 Infographic by Boster Bio

All MRGPRX3 Products

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Product

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Specificity

Applications

Price

Anti-MRGX3 MRGPRX3 Antibody

Human

ELISA, IF, WB

$380
Cat # A14574
100ul

MRGX3 (MRGPRX3) (NM_054031) Human Over-expression Lysate

Human

$628
Cat # LS117195
100 µg

MRGPRX3 Overview

Facts about Mas-related G-protein coupled receptor member X3.

MRGPRX3 3D structure. Source: alphafold

Mas-related G-protein coupled receptor member X3 (MRGPRX3)

Orphan receptor. Probably involved in the use of nociceptive neurons.

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).

Gene Information

Human
Gene Name:	MRGPRX3
Uniprot:	Q96LB0
Entrez:	117195

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor MRGX3; G protein-coupled receptor SNSR2; GPCR; mas-related GPCR member X3; MAS-related GPR, member X3; mas-related G-protein coupled receptor member X3; MRGPRX3; MRGX3; MRGX3G protein-coupled receptor SNSR1; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2

Molecular Weight

Mass (kDA):
36.483 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (18120955..18138488)

Tissue Specificity

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Edema
Parakeratosis
Skin Abnormalities

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MRGPRX3

References

PMID: 11551509 by Dong X., et al. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

PMID: 11850634 by Lembo P.M.C., et al. Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs.