MRGPRX2 Antibodies

AND MRGPRX2 ELISA kits, MRGPRX2 Proteins

Many biological assays use antibodies to detect MRGPRX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MRGPRX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MRGPRX2 antibodies...

We validate the specificity of these antibodies to MRGPRX2 by testing them on tissues known to express MRGPRX2 positively and negatively. Browse below to find the MRGPRX2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MRGPRX2 Infographic by Boster Bio

All MRGPRX2 Products

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Anti-MRGX2 MRGPRX2 Antibody

Human

ELISA, WB

$380
Cat # A06962
100ul

MRGPRX2 Overview

Facts about Mas-related G-protein coupled receptor member X2.

MRGPRX2 3D structure. Source: alphafold

Mas-related G-protein coupled receptor member X2 (MRGPRX2)

Mast cell-specific receptor for basic secretagogues, i.e.

cationic amphiphilic drugs, in addition to endo- or exogenous peptides, comprising a simple head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules comprising a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), such as tubocurarine and atracurium.

Gene Information

Human
Gene Name:	MRGPRX2
Uniprot:	Q96LB1
Entrez:	117194

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

MAS-related GPR, member X2; mas-related G-protein coupled receptor member X2; MRGPRX2; MRGX2; MRGX2G protein-coupled receptor MRGX2

Molecular Weight

Mass (kDA):
37.099 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (19054455..19060717, complement)

Tissue Specificity

Mainly expressed in mast cells. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion (PubMed:12915402). Detected in blood vessels, scattered lymphocytes, and gastrointestinal ganglia (at protein level) (PubMed:16161007).