MRGPRX1 Antibodies

AND MRGPRX1 ELISA kits, MRGPRX1 Proteins

Many biological assays use antibodies to detect MRGPRX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MRGPRX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MRGPRX1 antibodies...

We validate the specificity of these antibodies to MRGPRX1 by testing them on tissues known to express MRGPRX1 positively and negatively. Browse below to find the MRGPRX1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MRGPRX1 Infographic by Boster Bio

All MRGPRX1 Products

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Product

Figures

Specificity

Applications

Price

Anti-MRGX1/MRGPRX1 Antibody Picoband®

1 Q&As

Rat

IHC, WB

$370
Cat # PA1208
100 μg/vial

Anti-MRGX1 MRGPRX1 Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$335
Cat # A30840
100ul

MRGPRX1 Overview

Facts about Mas-related G-protein coupled receptor member X1.

MRGPRX1 3D structure. Source: alphafold

Mas-related G-protein coupled receptor member X1 (MRGPRX1)

Orphan receptor. Probably involved in the function of nociceptive neurons.

Potently triggered by enkephalins such as BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

Gene Information

Human
Gene Name:	MRGPRX1
Uniprot:	Q96LB2
Entrez:	259249

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor MRGX1; GPCR; MAS-related GPR, member X1; mas-related G-protein coupled receptor member X1; MRGX1; MRGX1G protein-coupled receptor SNSR3; Sensory neuron-specific G-protein coupled receptor 3/4; SNSR3; SNSR4

Molecular Weight

Mass (kDA):
36.25 kDA

Genomic Context


Human

Location:	11p15.1\|11
Sequence:	11; NC_000011.10 (18933813..18935002, complement)

Tissue Specificity

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Pruritus
Disease Of Adrenal Medulla
Hyperalgesia
Welts
Pain
Dysesthesia

PTMs

Cleavage

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MRGPRX1

References

PMID: 11551509 by Dong X., et al. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

PMID: 11850634 by Lembo P.M.C., et al. Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs.