MPP4 Antibodies

AND MPP4 ELISA kits, MPP4 Proteins

Many biological assays use antibodies to detect MPP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPP4 antibodies...

We validate the specificity of these antibodies to MPP4 by testing them on tissues known to express MPP4 positively and negatively. Browse below to find the MPP4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MPP4 Infographic by Boster Bio

All MPP4 Products

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MPP4 (NM_033066) Human Over-expression Lysate

Human

$960
Cat # LS058538
100 µg

MPP4 Overview

Facts about MAGUK p55 subfamily member 4.

MPP4 3D structure. Source: alphafold

MAGUK p55 subfamily member 4 (MPP4)

May play a role in retinal photoreceptors development. .

Gene Information

Human
Gene Name:	MPP4
Uniprot:	Q96JB8
Entrez:	58538

Family

Belongs to:

MAGUK family

Alternative Names

ALS2CR5; large homolog 6; MAGUK p55 subfamily member 4; membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)

Molecular Weight

Mass (kDA):
72.779 kDA

Genomic Context


Human

Location:	2q33.1
Sequence:	2; NC_000002.12 (201644874..201700263, complement)

Tissue Specificity

Expressed in the retina (at protein level). Highly expressed in the retina. Lower amounts are detected in brain, testis, ARPE-19, RPE/choroid and fetal eye. Isoform 5 is retina-specific.

Subcellular Localizations

Cytoplasm. Detected at the outer limiting membrane (OLM) and in the outer plexiform layer (OPL) of the retina. At the OLM, detected apical to the adherens junction (AJ).

Diseases

Retinitis Pigmentosa
Retinal Diseases
Tissue Adhesions
Amaurosis
Retinal Degeneration
Gaucher Disease
Leber Congenital Amaurosis
Cell Invasion
Bladder Neoplasm
Melanoma
Malignant Neoplasm Of Breast
Kyphosis Deformity Of Spine

Dystrophy
Blind Vision
Malignant Neoplasms
Disorder Of Eye
Congenital Thrombocytopenia
Neoplasms

Pathways

Localization
Translation
Cell Adhesion
Synaptic Transmission
Transport
Cell Migration
Cell Proliferation
Signal Transmission
Receptor Clustering
Cell Division

Cell Motility
Cellular Localization
Cell Death
Cell Cycle
Delamination

PTMs

Palmitoylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPP4

References

PMID: 11414766 by Stoehr H., et al. Cloning and characterization of the human retina-specific gene MPP4, a novel member of the p55 subfamily of MAGUK proteins.

PMID: 11586298 by Hadano S., et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.