RNA helicase Mov10l1 Antibodies

AND MOV10L1 ELISA kits, RNA helicase Mov10l1 Proteins

Many biological assays use antibodies to detect RNA helicase Mov10l1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNA helicase Mov10l1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNA helicase Mov10l1 antibodies...

We validate the specificity of these antibodies to RNA helicase Mov10l1 by testing them on tissues known to express MOV10L1 positively and negatively. Browse below to find the MOV10L1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MOV10L1 Infographic by Boster Bio

All MOV10L1 Products

Product

Figures

Specificity

Applications

Price

Anti-RNA helicase Mov10l1 MOV10L1 Antibody

7 Q&As

Human

$399
Cat # A09677
100μl

Anti-RNA helicase Mov10l1 MOV10L1 Antibody

Human

ELISA, IHC, WB

$380
Cat # A09677-1
100ul

MOV10L1 (NM_018995) Human Over-expression Lysate

Human

$960
Cat # LS054456
100 µg

MOV10L1 Overview

Facts about RNA helicase Mov10l1.

MOV10L1 3D structure. Source: alphafold

RNA helicase Mov10l1 (MOV10L1)

ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and stop their mobilization, which is essential for germline integrity. Acts through the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and modulates the methylation and subsequent repression of transposons.

Involved in the principal piRNA metabolic process. Specifically binds to piRNA precursors and promotes the creation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins.

Gene Information

Human
Gene Name:	MOV10L1
Uniprot:	Q9BXT6
Entrez:	54456

Family

Belongs to:

DNA2/NAM7 helicase family

Alternative Names

DJ402G11.8; DKFZp434B0717; EC 3.6.1; EC 3.6.4.13; FLJ33421; Moloney leukemia virus 10-like protein 1; Mov10 (mouse)-like 1; Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse); Mov10-like 1; MOV10-like protein 1; putative helicase Mov10l1

Molecular Weight

Mass (kDA):
135.293 kDA

Genomic Context


Human

Location:	22q13.33
Sequence:	22; NC_000022.11 (50090006..50161705)

Tissue Specificity

Isoform 1: Specifically expressed in testis.

Subcellular Localizations

Cytoplasm. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.

Diseases

Infertility
Hypertrophy
Male Infertility
Ovarian Cysts
Precocious Puberty
Azoospermia
Cryptorchidism

Genomic Instability
Female Infertility

Pathways

Cell Cycle
Cell Death
Heart Development
Pachytene
Meiosis
Cell Proliferation
Aging
Dna Methylation
Stem Cell Maintenance
Spermatogenesis
Senescence
Methylation

Dna Replication
Prophase
Sarcomere Organization
Meiosis I
Rna Processing
Rna Interference

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MOV10L1

References

PMID: 11279525 by Wang P.J., et al. An abundance of X-linked genes expressed in spermatogonia.