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- Table of Contents
Facts about ATPase MORC2.
Down-regulates CA9 expression (PubMed:20110259). .
Human | |
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Gene Name: | MORC2 |
Uniprot: | Q9Y6X9 |
Entrez: | 22880 |
Belongs to: |
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No superfamily |
AC004542.C22.1; KIAA0852; MORC family CW-type zinc finger 2; MORC family CW-type zinc finger protein 2; ZCW3; ZCWCC1; Zinc finger CW-type coiled-coil domain protein 1; zinc finger, CW type with coiled-coil domain 1; zinc finger, CW-type with coiled-coil domain 1
Mass (kDA):
117.823 kDA
Human | |
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Location: | 22q12.2 |
Sequence: | 22; NC_000022.11 (30925130..30968774, complement) |
Highly expressed in smooth muscle, pancreas and testis.
Nucleus. Cytoplasm, cytosol. Chromosome. Nucleus matrix. Mainly located in the nucleus (PubMed:20225202). Upon phosphorylation at Ser-739, recruited to damaged chromatin (PubMed:23260667).
PMID: 20225202 by Wang G.L., et al. Identification and expression analysis of a novel CW-type zinc finger protein MORC2 in cancer cells.
PMID: 20110259 by Shao Y., et al. Involvement of histone deacetylation in MORC2-mediated down- regulation of carbonic anhydrase IX.