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ZHX2 Antibodies
AND ZHX2 ELISA kits, ZHX2 Proteins
Many biological assays use antibodies to detect ZHX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZHX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZHX2 antibodies...
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ZHX2 Infographic by Boster Bio
All ZHX2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$523
Cat # M05837
100 µl
Cat # M05837
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M05837-1
100 μl/vial
Cat # M05837-1
100 μl/vial
ZHX2 Overview
Facts about Zinc fingers and homeoboxes protein 2.
Zinc fingers and homeoboxes protein 2 (ZHX2)
Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956).
May play a role in retinal development where it modulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | ZHX2 |
| Uniprot: | Q9Y6X8 |
| Entrez: | 22882 |
Family
| Belongs to: |
|---|
| ZHX family |
Alternative Names
zona pellucida glycoprotein 2 (sperm receptor); Zona pellucida glycoprotein 2; zona pellucida glycoprotein ZP2; Zona pellucida protein A; zona pellucida sperm-binding protein 2; Zp-2; ZPA
Molecular Weight
Mass (kDA):
92.307 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q24.13 |
| Sequence: | 8; NC_000008.11 (122781655..122974514) |
Tissue Specificity
Ubiquitously expressed. Expressed in podocytes.
Subcellular Localizations
Nucleus. Colocalizes with EFNB1 intracellular domain in the nucleus.
Diseases
- Liver Carcinoma
- Carcinoma
- Malignant Neoplasms
- Neoplasms
- Liver Neoplasms
- Malignant Neoplasm Of Liver
- Sclerosis
- Hemoglobin F Disease
- Carcinogenesis
- Multiple Myeloma
- Lymphoma
- Renal Glomerular Disease
Interacting Proteins
- ZHX1
Pathways
- Localization
- Cell Cycle
- Chromatin Remodeling
- Cell Proliferation
- Gene Silencing
- Cell Development
- Immune Response
- Proteolysis
- Neurogenesis
- Liver Development
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZHX2
bosterbio.com/bosterbio-gene-info-cards/ZHX2
References
PMID: 12741956 by Kawata H., et al. Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.
PMID: 14659886 by Kawata H., et al. The mouse zinc-fingers and homeoboxes (ZHX) family: ZHX2 forms a heterodimer with ZHX3.