Multimerin-2 Antibodies

AND MMRN2 ELISA kits, Multimerin-2 Proteins

Many biological assays use antibodies to detect Multimerin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Multimerin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Multimerin-2 antibodies...

We validate the specificity of these antibodies to Multimerin-2 by testing them on tissues known to express MMRN2 positively and negatively. Browse below to find the MMRN2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MMRN2 Infographic by Boster Bio

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Multimerin 2 (MMRN2) (NM_024756) Human Over-expression Lysate

Human

$628
Cat # LS079812
100 µg

MMRN2 Overview

Facts about Multimerin-2.

MMRN2 3D structure. Source: alphafold

Multimerin-2 (MMRN2)

Inhibits endothelial cells motility and functions as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA. .

Gene Information

Human
Gene Name:	MMRN2
Uniprot:	Q9H8L6
Entrez:	79812

Family

Belongs to:

No superfamily

Alternative Names

Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3EMILIN-3; EMILIN3; EMILIN-like protein EndoGlyx-1; EndoGlyx-1 p125/p140 subunit; Endoglyx-1; FLJ13465; MMRN2; multimerin 2; multimerin-2

Molecular Weight

Mass (kDA):
104.409 kDA

Genomic Context


Human

Location:	10q23.2
Sequence:	10; NC_000010.11 (86935540..86970480, complement)

Tissue Specificity

Endothelium.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Cell Transformation, Neoplastic
Tumor Angiogenesis
Malignant Neoplasms
Neoplasms
Pathologic Neovascularization

Pathways

Angiogenesis
Localization

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMRN2

References

PMID: 11559704 by Christian S., et al. Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium.

PMID: 22020326 by Lorenzon E., et al. MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway.