MICA Antibodies

AND MICA ELISA kits, MICA Proteins

Many biological assays use antibodies to detect MICA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MICA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MICA antibodies...

We validate the specificity of these antibodies to MICA by testing them on tissues known to express MICA positively and negatively. Browse below to find the MICA antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: PPP1R2P1

MICA Infographic by Boster Bio

All MICA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MICA Antibody Picoband®

4 Q&As

Human

$370
Cat # PB9612
100 μg/vial

Human MICA ELISA Kit PicoKine®

4 Q&As

Human

ELISA

$499
Cat # EK0812
96 wells/kit, with removable strips.

Anti-MICA Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A01366
0.1 mg

Anti-MICA Antibody

Human, Mouse, Rat

$405
Cat # A01366-1
100ul

MICA (NM_001177519) Human Recombinant Protein

$1062
Cat # PROTQ29983
20 µg

Anti-MICA Rabbit Monoclonal Antibody

Human

$370
Cat # M01366
100 μl/vial

MICA Overview

Facts about MHC class I polypeptide-related sequence A.

MICA 3D structure. Source: alphafold

MHC class I polypeptide-related sequence A (MICA)

Appears to have no function in antigen presentation. Acts as a stress-induced self-antigen that's recognized by gamma delta T- cells.

Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Gene Information

Human
Gene Name:	MICA
Uniprot:	Q29983
Entrez:	100507436

Family

Belongs to:

MHC class I family

Alternative Names

FLJ60820; MGC111087; MICA; PERB11.1

Molecular Weight

Mass (kDA):
42.915 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (31400711..31415315)

Tissue Specificity

Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cytoplasm. Expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Infection with human adenovirus 5 suppresses cell surface expression due to the adenoviral E3-19K protein which causes retention in the endoplasmic reticulum.