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- Table of Contents
Facts about Protein MGARP.
Participates in the translocation of TRAK2/GRIF1 in the cytoplasm into the mitochondrion. Plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
Mouse | |
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Gene Name: | Mgarp |
Uniprot: | Q8VI64 |
Entrez: | 67749 |
Belongs to: |
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No superfamily |
chromosome 4 open reading frame 49; hypoxia up-regulated mitochondrial movement regulator; MGC125827; MGC125828; OSAP
Mass (kDA):
29.925 kDA
Mouse | |
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Location: | 3|3 C |
Sequence: | 3; |
Expressed in the ovary, testis, brain, adrenal glands and the compartments of the visual nervous system. Expressed in corneal endothelium (CE) (at protein level). Expressed in steroidogenic tissues with the highest level of expression observed in the adrenal gland. Weakly expressed in placenta. Weakly expressed in astrocytes and neurons under normoxia. Strongly expressed in astrocytes and neurons under hypoxia. Expressed in each layer of the retina, with particularly higher staining in the inner segment of the photoreceptor (IS), the outer plexiform layer (OPL) and the ganglion cell layer (GCL).
PMID: 10919256 by Hennebold J.D., et al. Ovary-selective genes I: the generation and characterization of an ovary-selective complementary deoxyribonucleic acid library.
PMID: 16565373 by Kinouchi R., et al. Distribution of CESP-1 protein in the corneal endothelium and other tissues.